A COMBINATION OF EXTREME ENVIRONMENTAL CONDITIONS FAVOR THE PREVALENCE OF ENDOSPORE-FORMING FIRMICUTES




Hemophagocytic lymphohistiocytosis: a rare diagnosis, an even rarer opportunity to appraise our understanding of the immune system

The syndrome identified as hemophagocytic lymphohistiocytosis (HLH) poses a rather difficult challenge to the physician.HLH was initially described as a familial disorder,1 which was later associated with various genetic defects that affect the cytotoxic machinery of Fridge Control Case Assy CD8+ T and NK cells,2 but it also occurs sporadically, us

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Intra-operative cerebrospinal fluid sampling versus post-operative lumbar puncture for detection of leptomeningeal disease in malignant paediatric brain tumours.

Leptomeningeal disease is a feared sequelae of malignant paediatric brain tumours.Current methods for its detection is the combined use of cranio-spinal MRI, and CSF cytology from a post-operative lumbar puncture.In this study, the authors hypothesize that CSF taken at the start of surgery, either from an external ventricular drain or neuroendoscop

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